What percent of the population have two different colored eyes ?

Heterochromia, the condition where a person has two different colored eyes, is extremely rare. It affects less than 1% of the world's population, which translates to fewer than 78 million people globally24. In the United States, the occurrence is even lower, with about 6 in every 10,000 people having different colored irises4. An older study concluded that the occurrence rate for any type of heterochromia was about 0.26%, and complete heterochromia in the U.S. population is only about 0.06%4.